Methoxetamine

Buy Methoxetamine (MXE) Online

• Methoxetamine (abbreviated as MXE) is a novel psychoactive substance that is emerging on the Internet and induces dissociative effects and acute toxicity.
• MXE acts behaviourally as a typical dissociative anesthetic with stimulant and anxiogenic effects at lower doses, sedative/anesthetic effects at higher doses, and as a disruptor of sensorimotor gating.
• Its pharmacological effects have not yet been adequately investigated, but recently published articles show, that MXE differentially affected motor activity, behavior, and emotional states in rats, depending on the dose tested.
• This drug acts mainly as N-methyl-D-aspartate (NMDA) receptor antagonist and a serotonin reuptake inhibitor.

Details about MXE:

• Like other psychoactive drugs, methoxetamine high is described as pleasurable.
• And includes stimulant, relaxant, and dissociative effects.
• MXE has unpredictable and intense side effects. Particularly with higher doses—that are extremely unpleasant both physically and psychologically.
• This is sometimes called an m-hole.
• Hospital reports show that, while people can recover from MXE drug toxicity.
• This recovery period can require several days of hospitalization. Treatment includes detox medication, intravenous fluids, and respiratory support.
• In addition, news stories have blamed several deaths on the consumption of MXE.

Physical properties:

• The hydrochloride salt of methoxetamine is a white, odorless crystalline powder at room temperature.
• A physical description of the freebase form could not be found in the readily accessible literature.

Pharmacology:

• In research examining the pharmacological profile, data suggests that methoxetamine has an affinity for the N-methyl-D-aspartate (NMDA) receptor and acts as an antagonist.
• Also, it is similar to the related ketamine but it has a longer duration of action than ketamine.
• In addition similarly to ketamine, methoxetamine also involves dopamine and serotonin reuptake inhibition.
• No studies have been performed examining the pharmacology and mode of action of methoxetamine in humans.

Pharmacokinetics:

• There are no published formal animal or human studies examining its pharmacokinetic properties.